Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis.

Tuberculosis (TB) destroys lung tissues and this immunopathology is mediated in part by Matrix Metalloproteinases (MMPs). There are no data on the relationship between local tissue MMPs concentrations, anti-tuberculosis therapy and sputum conversion.Induced sputum was collected from 68 TB patients a...

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Bibliographic Details
Main Authors: Cesar A Ugarte-Gil, Paul Elkington, Robert H Gilman, Jorge Coronel, Liku B Tezera, Antonio Bernabe-Ortiz, Eduardo Gotuzzo, Jon S Friedland, David A J Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3632571?pdf=render