Self-Organization of Genome Expression from Embryo to Terminal Cell Fate: Single-Cell Statistical Mechanics of Biological Regulation

Self-Organization of Genome Expression from Embryo to Terminal Cell Fate: Single-Cell Statistical Mechanics of Biological Regulation

A statistical mechanical mean-field approach to the temporal development of biological regulation provides a phenomenological, but basic description of the dynamical behavior of genome expression in terms of autonomous self-organization with a critical transition (Self-Organized Criticality: SOC). T...

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Bibliographic Details
Main Authors: Alessandro Giuliani, Masa Tsuchiya, Kenichi Yoshikawa
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Entropy
Subjects:
early embryo development
reprogramming
single-cell differentiation
single-cell genome dynamics
self-organization
autonomous self-organized criticality
genome avalanche
statistical thermodynamics
critical transition state
Online Access:https://www.mdpi.com/1099-4300/20/1/13

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https://www.mdpi.com/1099-4300/20/1/13

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