Epigenome-wide association study on asthma and chronic obstructive pulmonary disease overlap reveals aberrant DNA methylations related to clinical phenotypes

Epigenome-wide association study on asthma and chronic obstructive pulmonary disease overlap reveals aberrant DNA methylations related to clinical phenotypes

Abstract We hypothesized that epigenetics is a link between smoking/allergen exposures and the development of Asthma and chronic obstructive pulmonary disease (ACO). A total of 75 of 228 COPD patients were identified as ACO, which was independently associated with increased exacerbations. Microarray...

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Bibliographic Details
Main Authors: Yung-Che Chen, Ying-Huang Tsai, Chin-Chou Wang, Shih-Feng Liu, Ting-Wen Chen, Wen-Feng Fang, Chiu-Ping Lee, Po-Yuan Hsu, Tung-Ying Chao, Chao-Chien Wu, Yu-Feng Wei, Huang-Chih Chang, Chia-Cheng Tsen, Yu-Ping Chang, Meng-Chih Lin, Taiwan Clinical Trial Consortium of Respiratory Disease (TCORE) group
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83185-1

Internet

https://doi.org/10.1038/s41598-021-83185-1

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