Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA.

Secondary metabolites, including toxins and melanins, have been implicated as virulence attributes in invasive aspergillosis. Although not definitively proved, this supposition is supported by the decreased virulence of an Aspergillus fumigatus strain, DeltalaeA, that is crippled in the production o...

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Bibliographic Details
Main Authors: Robyn M Perrin, Natalie D Fedorova, Jin Woo Bok, Robert A Cramer, Jennifer R Wortman, H Stanley Kim, William C Nierman, Nancy P Keller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030050