DNA Polymerases Drive DNA Sequencing-by-Synthesis Technologies: Both Past and Present

Next-generation sequencing (NGS) technologies have revolutionized modern biological and biomedical research. The engines responsible for this innovation are DNA polymerases; they catalyze the biochemical reaction for deriving template sequence information. In fact, DNA polymerase has been a cornerst...

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Bibliographic Details
Main Author: Cheng-Yao eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00305/full