Oleacein Attenuates the Pathogenesis of Experimental Autoimmune Encephalomyelitis through Both Antioxidant and Anti-Inflammatory Effects

Oleacein Attenuates the Pathogenesis of Experimental Autoimmune Encephalomyelitis through Both Antioxidant and Anti-Inflammatory Effects

Oxidative stress and proinflammatory cytokines are factors affecting multiple sclerosis (MS) disease progression. Oleacein (OLE), an olive secoiridoid, possesses powerful antioxidant and anti-inflammatory activities, which suggests its potential application to treat neuroinflammatory disorders. Here...

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Bibliographic Details
Main Authors: Beatriz Gutiérrez-Miranda, Isabel Gallardo, Eleni Melliou, Isabel Cabero, Yolanda Álvarez, Prokopios Magiatis, Marita Hernández, María Luisa Nieto
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
EAE
multiple sclerosis
inflammation
cytokines
oleacein
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/9/11/1161

Internet

https://www.mdpi.com/2076-3921/9/11/1161

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