Detrimental Effect of Sitagliptin Induced Autophagy on Multiterritory Perforator Flap Survival

Multiterritory perforator flap survival is commonly applied in surgical tissue reconstructions and covering of large skin defects. However, multiple risk factors such as ischemia, reperfusion injury, and apoptosis after reconstructive surgeries cause necrosis in distal parts with outcomes ranging fr...

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Bibliographic Details
Main Authors: Zhengtai Chen, Chenxi Zhang, Haiwei Ma, Zihuai Huang, Jiafeng Li, Junshen Lou, Baolong Li, Qi Tu, Weiyang Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00951/full