Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice.

BACKGROUND: The zoonotic pathogen Campylobacter jejuni is a leading cause of bacterial foodborne enterocolitis in humans worldwide. The understanding of immunopathology underlying human campylobacteriosis is hampered by the fact that mice display strong colonization resistance against the pathogen d...

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Bibliographic Details
Main Authors: Lea-Maxie Haag, André Fischer, Bettina Otto, Rita Plickert, Anja A Kühl, Ulf B Göbel, Stefan Bereswill, Markus M Heimesaat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3341396?pdf=render