Impaired Skeletal Muscle Branched-Chain Amino Acids Catabolism Contributes to Their Increased Circulating Levels in a Non-Obese Insulin-Resistant Fructose-Fed Rat Model

Elevated plasma branched-chain amino acids (BCAA) levels are often observed in obese insulin-resistant (IR) subjects and laboratory animals. A reduced capacity of the adipose tissues (AT) to catabolize BCAA has been proposed as an explanation, but it seems restricted to obesity models of genetically...

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Bibliographic Details
Main Authors: Jérémie David, Dominique Dardevet, Laurent Mosoni, Isabelle Savary-Auzeloux, Sergio Polakof
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/2/355