How do Uremic Toxins Affect the Endothelium?

Uremic toxins can induce endothelial dysfunction in patients with chronic kidney disease (CKD). Indeed, the structure of the endothelial monolayer is damaged in CKD, and studies have shown that the uremic toxins contribute to the loss of cell–cell junctions, increasing permeability. Membrane protein...

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Bibliographic Details
Main Authors: Regiane Stafim da Cunha, Andressa Flores Santos, Fellype Carvalho Barreto, Andréa Emilia Marques Stinghen
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/6/412