Synthesis of eicosa-2-trans-8,11,14-all cis-tetraenoic acid-3-14C and dl-3-hydroxy eicosa-8,11,14-all cis-trienoic acid-3-14C

A general procedure for the synthesis of 2-trans polyenoic fatty acids and of dl-3-hydroxypolyenoic acids is described. The 2-trans acids are prepared by LiAlH4 reduction of a suitable polyenoic fatty acid ester to the alcohol, formation of the tosylate, oxidation to the aldehyde, and Doebner conden...

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Bibliographic Details
Main Authors: W. Stoffel, H.D. Pruss
Format: Article
Language:English
Published: Elsevier 1967-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520401373