Microbial Genomics as a Catalyst for Targeted Antivirulence Therapeutics

Microbial Genomics as a Catalyst for Targeted Antivirulence Therapeutics

Virulence arresting drugs (VAD) are an expanding class of antimicrobial treatment that act to “disarm” rather than kill bacteria. Despite an increasing number of VAD being registered for clinical use, uptake is hampered by the lack of methods that can identify patients who are most likely to benefit...

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Bibliographic Details
Main Authors: Vitali Sintchenko, Verlaine Timms, Eby Sim, Rebecca Rockett, Nathan Bachmann, Matthew O'Sullivan, Ben Marais
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
Subjects:
virulence
genome sequence analysis
antibacterial treatment
surveillance
antimicrobial stewardship
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.641260/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.641260/full

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