Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction

Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction

Systems cancer biology analysis of calorie restriction (CR) mechanisms and pathways has not been carried out, leaving therapeutic benefits unclear. Using metadata analysis, we studied gene expression changes in normal mouse duodenum mucosa (DM) response to short-term (2-weeks) 25% CR as a biological...

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Bibliographic Details
Main Authors: Evan Maestri, Kalina Duszka, Vladimir A. Kuznetsov
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
duodenum mucosa
caloric restriction
gene expression
oncogenic pathways
immune response
telomere maintenance
Online Access:https://www.mdpi.com/2072-6694/13/13/3180

Internet

https://www.mdpi.com/2072-6694/13/13/3180

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