Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM

The organisation of plasma membrane receptors is important for their function. Here the authors combine lattice light-sheet microscopy with 3D single-molecule localisation microscopy (dSTORM) and single-particle tracking to study the distribution and motility of several surface receptors.

Bibliographic Details
Main Authors: Felix Wäldchen, Jan Schlegel, Ralph Götz, Michael Luciano, Martin Schnermann, Sören Doose, Markus Sauer
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14731-0