Low-Dose Ionizing Radiation Modulates Microglia Phenotypes in the Models of Alzheimer’s Disease

Low-Dose Ionizing Radiation Modulates Microglia Phenotypes in the Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of dementia. AD involves major pathologies such as amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. During the progression of AD, microglia can be polarized from anti-inflammatory M2 to pro-inflammatory M1 phenotype. The activation of...

Full description

Bibliographic Details
Main Authors: Sujin Kim, Hyunju Chung, Han Ngoc Mai, Yunkwon Nam, Soo Jung Shin, Yong Ho Park, Mi Joo Chung, Jong Kil Lee, Hak Young Rhee, Geon-Ho Jahng, Youngkyong Kim, Yu Jin Lim, Moonkyoo Kong, Minho Moon, Weon Kuu Chung
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
low-dose ionizing radiation
microglia
amyloid-beta
Alzheimer’s disease
TREM2, M1/M2
Online Access:https://www.mdpi.com/1422-0067/21/12/4532

Internet

https://www.mdpi.com/1422-0067/21/12/4532

Similar Items