AKAP150-mediated TRPV1 sensitization is disrupted by calcium/calmodulin

<p>Abstract</p> <p>Background</p> <p>The transient receptor potential vanilloid type1 (TRPV1) is expressed in nociceptive sensory neurons and is sensitive to phosphorylation. A-Kinase Anchoring Protein 79/150 (AKAP150) mediates phosphorylation of TRPV1 by Protein Kinase...

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Bibliographic Details
Main Authors: Shapiro Mark S, Belugin Sergei, Bal Manjot, Chaudhury Sraboni, Jeske Nathaniel A
Format: Article
Language:English
Published: SAGE Publishing 2011-05-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/7/1/34