Expression of Oct4 Protein in Astrocytic Tumours-Histopathologic and Immunohistochemical Study

Introduction: The majority of gliomas in adults are resistant to therapy. Therapy resistance has been attributed to the presence of cancer stem cells (CSCs). Oct4 is a transcription factor required for maintaining the pleuripotency and self-renewal of CSCs. It was found to be highly expressed in ast...

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Bibliographic Details
Main Authors: Menar M Al-Sayed Ayoub, Samar Abdel-Moneim Al-Sheikh, Lubna Omar Al-Farouk Abdel-Salam, Engy Samir Mohamed Abdel-Moneim Al-Hariry
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-11-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/12276/35035_CE[Ra1]_F(SL)_PF1(PG_SL)_PFA(HJ_SL)_PN(SL).pdf