A Genetic Polymorphism (rs17251221) in the Calcium-Sensing Receptor is Associated with Breast Cancer Susceptibility and Prognosis

A Genetic Polymorphism (rs17251221) in the Calcium-Sensing Receptor is Associated with Breast Cancer Susceptibility and Prognosis

Background: Calcium-sensing receptor (CaSR) is a typical G protein coupled receptor. The rs17251221 SNP is located in an intron of the CaSR gene, and the G allele is considered a gain of function mutation. Previous studies revealed that rs17251221 polymorphisms contribute to the risk of developing c...

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Bibliographic Details
Main Authors: Xiaoyan Li, Xiangnan Kong, Liyu Jiang, Tingting Ma, Shi Yan, Cunzhong Yuan, Qifeng Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Breast cancer
Susceptibility
Prognosis
Calcium-sensing receptor
Online Access:http://www.karger.com/Article/FullText/356659

Internet

http://www.karger.com/Article/FullText/356659

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