Antimicrobial Peptides Human Beta-Defensin-2 and -3 Protect the Gut During Candida albicans Infections Enhancing the Intestinal Barrier Integrity: In Vitro Study

The intestinal mucosa is composed of a monolayer of epithelial cells, which is highly polarized and firmly united to each other thanks to the presence of proteins complexes, called Tight junctions (TJs). Alteration of the mucus layer and TJs causes an increase in intestinal permeability, which can l...

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Bibliographic Details
Main Authors: Alessandra Fusco, Vittoria Savio, Maria Donniacuo, Brunella Perfetto, Giovanna Donnarumma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
gut
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.666900/full