The Cyclin-Dependent Kinase Ortholog pUL97 of Human Cytomegalovirus Interacts with Cyclins

The Cyclin-Dependent Kinase Ortholog pUL97 of Human Cytomegalovirus Interacts with Cyclins

The human cytomegalovirus (HCMV)-encoded protein kinase, pUL97, is considered a cyclin-dependent kinase (CDK) ortholog, due to shared structural and functional characteristics. The primary mechanism of CDK activation is binding to corresponding cyclins, including cyclin T1, which is the usual regula...

Full description

Bibliographic Details
Main Authors: Laura Graf, Rike Webel, Sabrina Wagner, Stuart T. Hamilton, William D. Rawlinson, Heinrich Sticht, Manfred Marschall
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Viruses
Subjects:
human cytomegalovirus
protein kinase pUL97
cyclins T1, B1 and A
protein-protein interaction
substrate phosphorylation
interaction-mediated regulation
Online Access:http://www.mdpi.com/1999-4915/5/12/3213

Internet

http://www.mdpi.com/1999-4915/5/12/3213

Similar Items