Changes in gene expression foreshadow diet-induced obesity in genetically identical mice.
High phenotypic variation in diet-induced obesity in male C57BL/6J inbred mice suggests a molecular model to investigate non-genetic mechanisms of obesity. Feeding mice a high-fat diet beginning at 8 wk of age resulted in a 4-fold difference in adiposity. The phenotypes of mice characteristic of hig...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-05-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1464831?pdf=render |