Signal transduction induced in Trypanosoma cruzi metacyclic trypomastigotes during the invasion of mammalian cells

Penetration of Trypanosoma cruzi into mammalian cells depends on the activation of the parasite's protein tyrosine kinase and on the increase in cytosolic Ca2+ concentration. We used metacyclic trypomastigotes, the T. cruzi developmental forms that initiate infection in mammalian hosts, to inve...

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Bibliographic Details
Main Authors: N. Yoshida, S. Favoreto Jr., A.T. Ferreira, P.M. Manque
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2000-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300003