Comparison of the oncogenomic landscape of canine and feline hemangiosarcoma shows novel parallels with human angiosarcoma

Angiosarcoma (AS) is a highly aggressive tumor of blood and lymphatic vessels in humans that shares many similarities with spontaneously occurring hemangiosarcoma (HSA) in dogs and cats. To investigate the genetic suitability of HSA as a model for AS, we sequenced ∼1000 cancer genes in 41 cases of H...

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Bibliographic Details
Main Authors: Kim Wong, Latasha Ludwig, Oscar Krijgsman, David J. Adams, Geoffrey A. Wood, Louise van der Weyden
Format: Article
Language:English
Published: The Company of Biologists 2021-07-01
Series:Disease Models & Mechanisms
Subjects:
dog
cat
Online Access:http://dmm.biologists.org/content/14/7/dmm049044