A Novel off-the-Shelf Trastuzumab-Armed NK Cell Therapy (ACE1702) Using Antibody-Cell-Conjugation Technology

A Novel off-the-Shelf Trastuzumab-Armed NK Cell Therapy (ACE1702) Using Antibody-Cell-Conjugation Technology

Natural killer (NK) cells harbor efficient cytotoxicity against tumor cells without causing life-threatening cytokine release syndrome (CRS) or graft-versus-host disease (GvHD). When compared to chimeric antigen receptor (CAR) technology, Antibody-Cell Conjugation (ACC) technology has been developed...

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Bibliographic Details
Main Authors: Hao-Kang Li, Ching-Wen Hsiao, Sen-Han Yang, Hsiu-Ping Yang, Tai-Sheng Wu, Chia-Yun Lee, Yan-Liang Lin, Janet Pan, Zih-Fei Cheng, Yan-Da Lai, Shih-Chia Hsiao, Sai-Wen Tang
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
natural killer cells
oNK
antibody-cell conjugation
ACE1702
cancer cell therapy
HER2
Online Access:https://www.mdpi.com/2072-6694/13/11/2724

Internet

https://www.mdpi.com/2072-6694/13/11/2724

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