Genomic DNA methylation changes in response to folic acid supplementation in a population-based intervention study among women of reproductive age.

Genomic DNA methylation changes in response to folic acid supplementation in a population-based intervention study among women of reproductive age.

Folate is a source of one-carbons necessary for DNA methylation, a critical epigenetic modification necessary for genomic structure and function. The use of supplemental folic acid is widespread however; the potential influence on DNA methylation is unclear. We measured global DNA methylation using...

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Bibliographic Details
Main Authors: Krista S Crider, Eoin P Quinlivan, Robert J Berry, Ling Hao, Zhu Li, David Maneval, Thomas P Yang, Sonja A Rasmussen, Quanhe Yang, Jiang-Hui Zhu, Dale J Hu, Lynn B Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3233549?pdf=render

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http://europepmc.org/articles/PMC3233549?pdf=render

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