DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.

Levels of omega-6 (n-6) and omega-3 (n-3), long chain polyunsaturated fatty acids (LcPUFAs) such as arachidonic acid (AA; 20:4, n-6), eicosapentaenoic acid (EPA; 20:5, n-3) and docosahexaenoic acid (DHA; 22:6, n-3) impact a wide range of biological activities, including immune signaling, inflammatio...

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Bibliographic Details
Main Authors: Timothy D Howard, Rasika A Mathias, Michael C Seeds, David M Herrington, James E Hixson, Lawrence C Shimmin, Greg A Hawkins, Matthew Sellers, Hannah C Ainsworth, Susan Sergeant, Leslie R Miller, Floyd H Chilton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026313?pdf=render