Heterozygous deficiency of endoglin decreases insulin and hepatic triglyceride levels during high fat diet.

Endoglin is a transmembrane auxiliary receptor for transforming growth factor-beta (TGF-beta) that is predominantly expressed on proliferating endothelial cells. It plays a wide range of physiological roles but its importance on energy balance or insulin sensitivity has been unexplored. Endoglin def...

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Bibliographic Details
Main Authors: Daniel Beiroa, Amparo Romero-Picó, Carmen Langa, Carmelo Bernabeu, Miguel López, José M López-Novoa, Ruben Nogueiras, Carlos Diéguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3545959?pdf=render