Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures.

While the effects of hypoxia on gene expression have been investigated in the CNS to some extent, we currently do not know what role epigenetics plays in the transcription of many genes during such hypoxic stress. To start understanding the role of epigenetic changes during hypoxia, we investigated...

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Bibliographic Details
Main Authors: Iain Hartley, Fuad F Elkhoury, Joo Heon Shin, Bin Xie, Xiangqun Gu, Yuan Gao, Dan Zhou, Gabriel G Haddad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3808424?pdf=render