ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis

ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis

Hepatic fibrosis is an inflammatory response that leads to liver cirrhosis in the most advanced condition. Liver cirrhosis is a leading cause of deaths associated with liver diseases; hence, understanding the underlying mechanisms of hepatic fibrosis is critical to develop effective therapies. Tripa...

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Bibliographic Details
Main Authors: Haina Xie, Dongyu Xie, Jingxian Zhang, Wenye Jin, Yue Li, Jun Yao, Zhiqiang Pan, Donghao Xie
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
TRIM37
SMAD7
NF-κB
hepatic fibrosis
hepatitis B virus
reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302432

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http://www.sciencedirect.com/science/article/pii/S2162253120302432

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