High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses

High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses

IntroductionLung diseases are an increasing global health burden affecting millions of people worldwide. Only a few new inhaled medicines have reached the market in the last 30 years, in part due to foamy alveolar macrophage (FAM) responses observed in pre-clinical rat studies. The induction mechani...

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Bibliographic Details
Main Authors: Ewelina Hoffman, Paulina Napieralska, Rhamiya Mahendran, Darragh Murnane, Victoria Hutter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
alveolar macrophages
foamy alveolar macrophages
macrophage morphometrics
vacuolation
cytokine activation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.611280/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.611280/full

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