A collection of integration-free iPSCs derived from Parkinson's disease patients carrying mutations in the GBA1 gene

A collection of integration-free iPSCs derived from Parkinson's disease patients carrying mutations in the GBA1 gene

Mutations in the GBA1 gene, which encodes the lysosomal enzyme Glucocerebrosidase1 are major risk factors for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). We have generated induced pluripotent stem cells (iPSCs) from fibroblasts of four PD patients carrying the N370S/wt or the...

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Bibliographic Details
Main Authors: Eva Rodríguez-Traver, Eva Díaz-Guerra, César Rodríguez, Pablo Fernández, Fabián Arenas, Marcos Araúzo-Bravo, María Orera, Jaime Kulisevsky, Rosario Moratalla, Carlos Vicario
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119301126

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http://www.sciencedirect.com/science/article/pii/S1873506119301126

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