A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

Summary: How are closely related lineages, including liver, pancreas, and intestines, diversified from a common endodermal origin? Here, we apply principles learned from developmental biology to rapidly reconstitute liver progenitors from human pluripotent stem cells (hPSCs). Mapping the formation o...

Full description

Bibliographic Details
Main Authors: Lay Teng Ang, Antson Kiat Yee Tan, Matias I. Autio, Su Hua Goh, Siew Hua Choo, Kian Leong Lee, Jianmin Tan, Bangfen Pan, Jane Jia Hui Lee, Jen Jen Lum, Christina Ying Yan Lim, Isabelle Kai Xin Yeo, Chloe Jin Yee Wong, Min Liu, Jueween Ling Li Oh, Cheryl Pei Lynn Chia, Chet Hong Loh, Angela Chen, Qingfeng Chen, Irving L. Weissman, Kyle M. Loh, Bing Lim
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
human liver development
pluripotent stem cells
progenitor
efficient differentiation
signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718301517

Internet

http://www.sciencedirect.com/science/article/pii/S2211124718301517

Similar Items