Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Human memory and marginal zone B cells share some features including CD27 expression and somatic hypermutation, but their lineage relationship is still unclear. Here the authors use mass cytometry and sequential clustering methods to show that, despite their shared features, memory and marginal zone...

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Bibliographic Details
Main Authors: Yuan Zhao, Mohamed Uduman, Jacqueline H. Y. Siu, Thomas J. Tull, Jeremy D. Sanderson, Yu-Chang Bryan Wu, Julian Q. Zhou, Nedyalko Petrov, Richard Ellis, Katrina Todd, Konstantia-Maria Chavele, William Guesdon, Anna Vossenkamper, Wayel Jassem, David P. D’Cruz, David J. Fear, Susan John, Dagmar Scheel-Toellner, Claire Hopkins, Estefania Moreno, Natalie L. Woodman, Francesca Ciccarelli, Susanne Heck, Steven H. Kleinstein, Mats Bemark, Jo Spencer
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06089-1

Internet

https://doi.org/10.1038/s41467-018-06089-1

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