Overexpression ofapoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted micethan in apoB-100-only mice

Overexpression ofapoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted micethan in apoB-100-only mice

The adaptive value of apolipoprotein B-48 (apoB-48), thetruncated form of apoB produced by the intestine, in lipid metabolism remainsunclear. We crossed human apoC-III transgenic mice with mice expressing eitherapoB-48 only (apoB48/48) or apoB-100 only(apoB100/100). Cholesterol levels were higher in...

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Bibliographic Details
Main Authors: Karin Conde-Knape, Kenta Okada, Rajasekhar Ramakrishnan, NeilS. Shachter
Format: Article
Language:English
Published: Elsevier 2004-12-01
Series:Journal of Lipid Research
Subjects:
apolipoproteins C
apolipoproteinsB
hyperglycemia
transgenic
postprandialperiod
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341031

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http://www.sciencedirect.com/science/article/pii/S0022227520341031

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