Gene-specific function prediction for non-synonymous mutations in monogenic diabetes genes.

The rapid progress of genomic technologies has been providing new opportunities to address the need of maturity-onset diabetes of the young (MODY) molecular diagnosis. However, whether a new mutation causes MODY can be questionable. A number of in silico methods have been developed to predict functi...

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Bibliographic Details
Main Authors: Quan Li, Xiaoming Liu, Richard A Gibbs, Eric Boerwinkle, Constantin Polychronakos, Hui-Qi Qu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4138110?pdf=render