Cellular contractility requires ubiquitin mediated proteolysis.

Cellular contractility requires ubiquitin mediated proteolysis.

BACKGROUND:Cellular contractility, essential for cell movement and proliferation, is regulated by microtubules, RhoA and actomyosin. The RhoA dependent kinase ROCK ensures the phosphorylation of the regulatory Myosin II Light Chain (MLC) Ser19, thereby activating actomyosin contractions. Microtubule...

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Bibliographic Details
Main Authors: Yuval Cinnamon, Oren Feine, Helfrid Hochegger, Alexander Bershadsky, Michael Brandeis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2705188?pdf=render

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http://europepmc.org/articles/PMC2705188?pdf=render

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