Polarized Secretion of APRIL by the Tonsil Epithelium Upon Toll-Like Receptor Stimulation

In mucosa such as tonsil, antibody-producing plasmocytes (PCs) lie in sub-epithelium space, which is thought to provide a suitable environment for their survival. A proliferation inducing ligand (APRIL) is one key survival factor for PCs present in this area. According to in situ staining, apical ep...

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Bibliographic Details
Main Authors: Nathalie Sturm, Melanie Quinterot, Jean-Philippe Guyot, Christian Righini, Willeke F. Daamen, Toin H. van Kuppevelt, Bertrand Huard
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.715724/full