Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation

Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation

Enhanced glucose utilization can be visualized in atherosclerotic lesions and may reflect a high glycolytic rate in lesional macrophages, but its causative role in plaque progression remains unclear. We observe that the activity of the carbohydrate-responsive element binding protein ChREBP is rapidl...

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Bibliographic Details
Main Authors: Vincent Sarrazy, Sophie Sore, Manon Viaud, Guylène Rignol, Marit Westerterp, Franck Ceppo, Jean-Francois Tanti, Rodolphe Guinamard, Emmanuel L. Gautier, Laurent Yvan-Charvet
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009651

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http://www.sciencedirect.com/science/article/pii/S2211124715009651

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