Selective genomic copy number imbalances and probability of recurrence in early-stage breast cancer.

A number of studies of copy number imbalances (CNIs) in breast tumors support associations between individual CNIs and patient outcomes. However, no pattern or signature of CNIs has emerged for clinical use. We determined copy number (CN) gains and losses using high-density molecular inversion probe...

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Bibliographic Details
Main Authors: Patricia A Thompson, Abenaa M Brewster, Do Kim-Anh, Veerabhadran Baladandayuthapani, Bradley M Broom, Mary E Edgerton, Karin M Hahn, James L Murray, Aysegul Sahin, Spyros Tsavachidis, Yuker Wang, Li Zhang, Gabriel N Hortobagyi, Gordon B Mills, Melissa L Bondy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3155554?pdf=render