Patient-specific factors influence somatic variation patterns in von Hippel–Lindau disease renal tumours

Patient-specific factors influence somatic variation patterns in von Hippel–Lindau disease renal tumours

Analysing multiple tumours from the same patient permits the study of the germline contribution to cancer. Here, the authors sequence multiple renal tumours from VHL patients and find that intra-patient tumours are clonally distinct but share some genetic features, suggesting that patient-specific f...

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Bibliographic Details
Main Authors: Suzanne S. Fei, Asia D. Mitchell, Michael B. Heskett, Cathy D. Vocke, Christopher J. Ricketts, Myron Peto, Nicholas J. Wang, Kemal Sönmez, W. Marston Linehan, Paul T. Spellman
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11588

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https://doi.org/10.1038/ncomms11588

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