Impact of frontline treatment approach on outcomes of myeloid blast phase CML

Impact of frontline treatment approach on outcomes of myeloid blast phase CML

Abstract Background The natural course of untreated chronic myeloid leukemia (CML) is progression to an aggressive blast phase. Even in the current era of BCR-ABL1 tyrosine kinase inhibitors (TKIs), the outcomes of blast phase CML remain poor with no consensus frontline treatment approach. Methods W...

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Bibliographic Details
Main Authors: Kapil Saxena, Elias Jabbour, Ghayas Issa, Koji Sasaki, Farhad Ravandi, Abhishek Maiti, Naval Daver, Tapan Kadia, Courtney D. DiNardo, Marina Konopleva, Jorge E. Cortes, Musa Yilmaz, Kelly Chien, Sherry Pierce, Hagop Kantarjian, Nicholas J. Short
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Hematology & Oncology
Subjects:
CML
Blast phase
Chemotherapy
Hypomethylating agent
TKI
Online Access:https://doi.org/10.1186/s13045-021-01106-1

Internet

https://doi.org/10.1186/s13045-021-01106-1

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