Catenin Alpha-2 Mutation Changes the Immune Microenvironment in Lung Adenocarcinoma Patients Receiving Immune Checkpoint Inhibitors

Catenin Alpha-2 Mutation Changes the Immune Microenvironment in Lung Adenocarcinoma Patients Receiving Immune Checkpoint Inhibitors

Background: Lung cancer has always been the most prevalent cancer. Lung adenocarcinoma (LUAD) is the most common lung cancer subtype and has a high tumor mutation rate. In addition to KRAS, EGFR, ALK, HER2, ROS1, and BRAF, which are known to have high mutation rates, we discovered some new mutated g...

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Bibliographic Details
Main Authors: Yang Wen, Anqi Lin, Weiliang Zhu, Ting Wei, Peng Luo, Linlang Guo, Jian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
CTNNA2
lung adenocarcinoma
immune checkpoint inhibitors
immune microenvironment
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.645862/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.645862/full

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