Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant.

Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant.

BACKGROUND: Inositol 1,4,5trisphosphate (IP(3)) and diacylglycerol (DAG) are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD) forms one class. Studies with functional inactivation of Pl...

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Bibliographic Details
Main Authors: Fabian Runkel, Maik Hintze, Sebastian Griesing, Marion Michels, Birgit Blanck, Kiyoko Fukami, Jean-Louis Guénet, Thomas Franz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378570?pdf=render

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http://europepmc.org/articles/PMC3378570?pdf=render

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