A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

Summary: Large-scale mapping of antigens and epitopes is pivotal for developing immunotherapies but challenging, especially for eukaryotic pathogens, owing to their large genomes. Here, we developed an integrated platform for genome phage display (gPhage) to show that unbiased libraries of the eukar...

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Bibliographic Details
Main Authors: André Azevedo Reis Teixeira, Luis Rodriguez Carnero, Andréia Kuramoto, Fenny Hui Fen Tang, Carlos Hernique Gomes, Natalia Bueno Pereira, Léa Campos de Oliveira, Regina Garrini, Jhonatas Sirino Monteiro, João Carlos Setubal, Ester Cerdeira Sabino, Renata Pasqualini, Walter Colli, Wadih Arap, Maria Júlia Manso Alves, Edécio Cunha-Neto, Ricardo José Giordano
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Parasitology
Sequence Analysis
Systems Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221005083

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http://www.sciencedirect.com/science/article/pii/S2589004221005083

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