DNA Synthesis during Endomitosis Is Stimulated by Insulin via the PI3K/Akt and TOR Signaling Pathways in the Silk Gland Cells of Bombyx mori

DNA Synthesis during Endomitosis Is Stimulated by Insulin via the PI3K/Akt and TOR Signaling Pathways in the Silk Gland Cells of Bombyx mori

Silk gland cells undergo multiple endomitotic cell cycles during silkworm larval ontogeny. Our previous study demonstrated that feeding is required for continued endomitosis in the silk gland cells of silkworm larvae. Furthermore, the insulin signaling pathway is closely related to nutritional sign...

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Bibliographic Details
Main Authors: Yaofeng Li, Xiangyun Chen, Xiaofang Tang, Chundong Zhang, La Wang, Peng Chen, Minhui Pan, Cheng Lu
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
Bombyx mori
silk gland
DNA synthesis
insulin signaling
Online Access:http://www.mdpi.com/1422-0067/16/3/6266

Internet

http://www.mdpi.com/1422-0067/16/3/6266

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