Impact of EZH2 polymorphisms on urothelial cell carcinoma susceptibility and clinicopathologic features.

The gene EZH2, the polycomb group protein enhancer of zeste 2, encodes a transcriptional repressor that also serves as a histone methyltransferase that is associated with progression to more advanced disease in a variety of malignancies. EZH2 expression level in urothelial cell carcinoma (UCC) is hi...

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Bibliographic Details
Main Authors: Yung-Luen Yu, Kuo-Jung Su, Ming-Ju Hsieh, Shian-Shiang Wang, Po-Hui Wang, Wei-Chun Weng, Shun-Fa Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3972169?pdf=render