Dexamethasone-Mediated Activation of Fibronectin Matrix Assembly Reduces Dispersal of Primary Human Glioblastoma Cells.

Dexamethasone-Mediated Activation of Fibronectin Matrix Assembly Reduces Dispersal of Primary Human Glioblastoma Cells.

Despite resection and adjuvant therapy, the 5-year survival for patients with Glioblastoma multiforme (GBM) is less than 10%. This poor outcome is largely attributed to rapid tumor growth and early dispersal of cells, factors that contribute to a high recurrence rate and poor prognosis. An understan...

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Bibliographic Details
Main Authors: Stephen Shannon, Connan Vaca, Dongxuan Jia, Ildiko Entersz, Andrew Schaer, Jonathan Carcione, Michael Weaver, Yoav Avidar, Ryan Pettit, Mohan Nair, Atif Khan, Ramsey A Foty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4540426?pdf=render

Internet

http://europepmc.org/articles/PMC4540426?pdf=render

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