Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression

Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression

Andrographolide (ANDRO) has been studied for its immunomodulation, anti-inflammatory, and neuroprotection effects. Because brain hypoxia is the most common factor of secondary brain injury after traumatic brain injury, we studied the role and possible mechanism of ANDRO in this process using hypoxia...

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Bibliographic Details
Main Authors: Juan Du, Chunyan Zhang, Xueqing Na, Aizhi Li, Qingfeng Zhang, Kezhong Li, Yongbo Ding
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Andrographolide
Hypoxia-injured astrocytes
JNK pathway
S100B
ATG5
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000600604&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000600604&lng=en&tlng=en

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