Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines

Objective: To assess and compare the cytotoxic, genotoxic, apoptotic and reactive oxygen species (ROS) generating effects of naringenin (NG) and its new derived compound naringenin-oxime (NG-Ox) on MCF-7, HT-29, PC-12 cancer and L-929 normal cell lines. Methods: The cells were incubated with differe...

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Bibliographic Details
Main Authors: Abdurrahim Kocyigit, Ismail Koyuncu, Murat Dikilitas, Fatemeh Bahadori, Baki Turkkan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-10-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169115309941