Identification of a missing link in the evolution of an enzyme into a transcriptional regulator.

Identification of a missing link in the evolution of an enzyme into a transcriptional regulator.

The evolution of transcriptional regulators through the recruitment of DNA-binding domains by enzymes is a widely held notion. However, few experimental approaches have directly addressed this hypothesis. Here we report the reconstruction of a plausible pathway for the evolution of an enzyme into a...

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Bibliographic Details
Main Authors: Gonzalo Durante-Rodríguez, José Miguel Mancheño, Germán Rivas, Carlos Alfonso, José Luis García, Eduardo Díaz, Manuel Carmona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602430?pdf=render

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http://europepmc.org/articles/PMC3602430?pdf=render

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